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The Yale Pediatric Thyroid Center

Research

Expanding our knowledge of the treatment and causes of pediatric thyroid disease is a major goal of the Yale Pediatrics Thyroid Center. Important contributions of our members include the identification of genes that cause thyroid cancer, optimization of treatment of childhood Grave's disease, the development of minimally invasive surgery approaches, and the development of new diagnostic approaches for thyroid disease and thyroid cancer.

Select publications by our members

Anthony T, Fong P, Goyal A, Saltzman WM, Moss RL, Breuer C. Development of a parathyroid hormone-controlled release system as a potential surgical treatment for hypoparathyroidism. J Pediatr Surg. 2005 Jan;40(1):81-5

Chen H, Dudley NE, Westra WH, Sadler GP, Udelsman R. Utilization of fine-needle aspiration in patients undergoing thyroidectomy at two academic centers across the Atlantic. World J Surg. 2003 Feb;27(2):208-11.

Garcia-Rostan G, Tallini G, Herrero A, D'Aquila TG, Carcangiu ML, Rimm DL. Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma. Cancer Res. 1999 Apr 15;59(8):1811-5.

Gill JR, Reyes-Mugica M, Iyengar S, Kidd KK, Touloukian RJ, Smith C, Keller MS, Genel M. Related Early presentation of metastatic medullary carcinoma in multiple endocrine neoplasia, type IIA: implications for therapy. J Pediatr. 1996 Sep;129(3):459-64.

McKee M. Operating on critically ill neonates: the OR or the NICU. Semin Perinatol. 2004 Jun;28(3):234-9.

Pappu S, Donovan P, Cheng D, Udelsman R. Sestamibi scans are not all created equally. Arch Surg. 2005 Apr;140(4):383-6.

Powers P, Dinauer C, Tuttle RM and Francis G. The MACIS Score Predicts Outcome for Children and Adolescents with Papillary Thyroid Cancer. J Pediatr Endocrinol Metab 2004; 17(3): 339-43.

Powers PA, Dinauer CA, Tuttle RM, Robie DK, McClellan DR, and Francis GL. Treatment of recurrent papillary thyroid carcinoma in children and adolescents. J Pediatr Endocrinol Metab 2003; 16:1033-1040.

Powers PA, Dinauer CA, Tuttle RM, and Francis GL. Tumor size and extent of disease at diagnosis predict the response to initial therapy for papillary thyroid carcinoma in children and adolescents. J Ped Endo & Metab 2003; 16(5): 693-702.

Rimm DL, Stastny JF, Rimm EB, Ayer S, Frable WJ. Comparison of the costs of fine-needle aspiration and open surgical biopsy as methods for obtaining a pathologic diagnosis. Cancer. 1997 Feb 25;81(1):51-6.

Rivkees SA, Bode HH, Crawford JD. Long term growth in juvenile acqui-red hypothyroidism: failure to achieve normal adult height. New England Journal of Medicine 318: 599-602, 1988.

Rivkees SA, Cornelius EA. Influence of iodine-131 dose on the outcome of hyperthyroidism in children. Pediatrics. 2003 111:745-9.

Rivkees SA, Sklar C, Freemark M. The Management of Graves’ Disease in Children with Special Emphasis on Radioiodine Treatment. J Clinical Endocrinology and Metabolism 83:3767-3776, 1998.

Udelsman R, Shaha AR. Is total thyroidectomy the best possible surgical management for well-differentiated thyroid cancer? Lancet Oncol. 2005 Jul;6(7):529-31.

Yusuf K, Reyes-Mugica M, Carpenter TO. Insular carcinoma of the thyroid in an adolescent: a case report and review of the literature. Curr Opin Pediatr. 2003 Oct;15(5):512-5.